Publications

Dhital B and Rodriguez-Bravo V. Mechanisms of chromosomal instability (CIN) tolerance in aggressive tumors: surviving the genomic chaos. Chromosome Res. 2023 Apr 14;31(2):15.Link to paper

Dhital B, Santasusagna S, Kirthika P, Xu M, Li P, Carceles-Cordon M, Soni RK, Li Z, Hendrickson RC, Schiewer MJ, Kelly WK, Sternberg CN, Luo J, Lujambio A, Cordon-Cardo C, Alvarez-Fernandez M, Malumbres M, Huang H, Ertel A, Domingo-Domenech J, Rodriguez-Bravo V. Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer. Cell Rep Med. Volume 4, Issue 2, 21 February 2023. Link to paper

Olivier T, Fernandez E, Labidi-Galy I, Dietrich PY, Rodriguez-Bravo V, Baciarello G, Fizazi K, Patrikidou A. Redefining cancer of unknown primary: Is precision medicine really shifting the paradigm?. Cancer Treat Rev. 2021 Jun;97:102204. doi: 10.1016/j.ctrv.2021.102204. Epub 2021 Apr 5. Link to paper

Carceles-Cordon M, Kelly WK, Gomella L, Knudsen KE, Rodriguez-Bravo V*, Domingo-Domenech J*. Cellular rewiring in lethal prostate cancer: the architect of drug resistance. Nat Rev Urology. 2020 May; 17 (5): 292-307. *(Corresponding author). Link to paper

Woo J, Santasusagna S, Banks J, Pastor-Lopez S, Yadav K, Carceles-Cordon M, Dominguez-Andres A, Den RB, Languino LR, Pippa R, Lallas CD, Lu-Yao G, Kelly WK, Knudsen KE, Rodriguez-Bravo V, Tewari AK, Prats JM, Leiby BE, Gomella LG, Domingo-Domenech J. Urine Extracellular Vesicle GATA2 mRNA Discriminates Biopsy Result in Men with Suspicion of Prostate Cancer. J Urology. 2020 Oct; 204(4):691-700. Link to paper

Rodriguez-Bravo V*, Pippa R, Song WM, Carceles-Cordon M, Dominguez-Andres A, Fujiwara N, Woo J, Koh AP, Ertel A, Lokareddy RK, Cuesta-Dominguez A, Kim RS, Rodriguez-Fernandez I, Li P, Gordon R, Hirschfield H, Prats JM, Reddy EP, Fatatis A, Petrylak DP, Gomella L, Kelly WK, Lowe SW, Knudsen KE, Galsky MD, Cingolani G, Lujambio A, Hoshida Y, Domingo-Domenech J*. Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import. Cell. 2018 Aug 23;174(5):1200-1215.e20. doi: 10.1016/j.cell.2018.07.015. Epub 2018 Aug 9. *(Corresponding author). Link to paper

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel. Mohr L, Carceles-Cordon M, Woo J, Cordon-Cardo C, Domingo-Domenech J, Rodriguez-Bravo V. J Vis Exp. 2017 Sep 8;(127). doi: 10.3791/56327. Link to paper

Maciejowski J, Drechsler H, Grundner-Culemann K, Ballister ER, Rodriguez-Rodriguez JA, Rodriguez-Bravo V, Jones MJK, Foley E, Lampson MA, Daub H, McAinsh AD, Jallepalli PV. Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation. Dev Cell. 2017 Apr 24;41(2):143-156.e6. doi: 10.1016/j.devcel.2017.03.025. Link to paper

Han D, Rodriguez-Bravo V, Charytonowicz E, Demicco E, Domingo-Domenech J, Maki RG, Cordon-Cardo C. Targeting sarcoma tumor-initiating cells through differentiation therapy. Stem Cell Res. 2017 Apr 13;21:117-123. doi: 10.1016/j.scr.2017.04.004. Link to paper

Lee SJ, Rodriguez-Bravo V, Kim H, Datta S, Foley EA.The PP2AB56 phosphatase promotes the association of Cdc20 with APC/C in mitosis. J Cell Sci. 2017 Apr 12. pii: jcs.201608. doi: 10.1242/jcs.201608. Link to paper

Rodriguez-Bravo V, Carceles-Cordon M, Hoshida Y, Cordon-Cardo C, Galsky MD, Domingo-Domenech. The role of GATA2 in lethal prostate cancer aggressiveness. Nat Rev Urol. 2016 Nov 22. doi: 10.1038/nrurol.2016.225. [Epub ahead of print] Review. Link to paper

Estrelania Williams, Veronica Rodriguez-Bravo, Uma Chippada-Venkata, Janis De Ia Iglesia-Vicente, Yixuan Gong, Matthew Galsky, William Oh, Carlos Cordon-Cardo, Josep Domingo-Domenech. Generation of prostate cancer patient derived xenograft models from circulating tumor cells. J Vis Exp. 2015 Oct 20;(105). Link to paper

Vidal SJ, Rodriguez-Bravo V, Quinn SA, Rodriguez-Barrueco R, Lujambio A, Williams E, Sun X, de la Iglesia-Vicente J, Lee A, Readhead B, Chen X, Galsky M, Esteve B, Petrylak DP, Dudley JT, Rabadan R, Silva JM, Hoshida Y, Lowe SW, Cordon-Cardo C, Domingo-Domenech J. A targetable GATA2 signaling axis confers aggressiveness in lethal prostate cancer. Cancer Cell. 2015 Feb 9;27(2):223-39. Cover and Preview. Link to paper

Rodriguez-Bravo V, Maciejowski J, Corona J, Kirkeby Buch H, Collin P, Kanemaki MT, Shah JV, Jallepalli PV. Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor. Cell. 2014 Feb 27;156(5):1017-31. Link to paper

Vidal SJ, Quinn SA, de la iglesia-Vicente J, Bonal DM, Rodriguez-Bravo V et al. Isolation of Cancer Stem Cells from Human Prostate Cancer Samples. J Vis Exp. 2014 Mar 14;(85). Link to paper

Vidal SJ, Rodriguez-Bravo V, Galsky M, Cordon-Cardo C, Domingo-Domenech J. Targeting Cancer Stem Cells to Suppress Acquired Chemotherapy Resistance. Oncogene. 2014 Sep 4;33(36):4451-63. Link to paper

Domingo-Domenech J, Vidal S.J, Rodriguez-Bravo V, Castillo-Martin M et al. Suppression of acquired Docetaxel resistance in prostate cancer through depletion of Notch and Hedgehog dependent tumor initiating cells. Cancer Cell. 2012 Sep 11;22(3):373-88. Link to paper

Burkard ME, Maciejowski J, Rodriguez-Bravo V, Repka M, et al. Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells. PLoS Biol. 2009 May 5;7(5):e1000111. Link to paper

Lindqvist A, Rodríguez-Bravo V, Medema RH. The decision to enter mitosis: feedback and redundancy in the mitotic entry network. J Cell Biol. 2009 Apr 20;185(2):193-202. Link to paper

Rodríguez-Bravo V, Guaita-Esteruelas S, Salvador N, Bachs O, Agell N. Different S/M checkpoint responses of tumor and non-tumor cell lines to DNA replication inhibition Cancer Res. 2007 Dec 15;67(24):11648-56. Link to paper

Rodríguez-Bravo V, Guaita-Esteruelas S, Florensa R, Bachs O, Agell N. Chk1 and Claspin–dependent but ATR/ATM and Rad17- independent DNA replication checkpoint response in HeLa cells. Cancer Res. 2006 Sep 1;66(17):8672-8679. Link to paper

​​