Lab Head Bio
BMB Department and Urology Department
Dr. Rodriguez-Bravo obtained her PhD in Pathology and Cell Biology (Summa Cum Laude) from the University of Barcelona in 2007, where she also received the Extraordinary Doctorate Award for her studies on the distinct DNA replication checkpoint mechanisms of tumor cells. During her postdoctoral training at the Experimental Oncology Department of the University Medical Center of Utrecht (UMC, The Netherlands) and at the Molecular and Cell Biology Programs of Memorial Sloan Kettering Cancer Center (MSKCC, New York), she specialized in the study of chromosome segregation during mitosis and the role of nuclear pores in genome integrity maintenance.
Her postdoctoral work allowed her to apply genome-editing techniques crucial to dissect the function of mitotic and nuclear pore proteins in chromosomal stability and resulted in the recognition with the Memorial Sloan Kettering Cancer Center Postdoctoral Research Award (Rodriguez-Bravo V et al. Cell, 2014).
The Rodriguez-Bravo Lab is NCI-funded and focuses on studying the intricate mechanisms regulating genome function, organization and integrity and the consequences of dysregulation in cancer aggressiveness. A main area of investigations is the study of nuclear pores-regulated functions in cancer (Rodriguez-Bravo V et al. Cell 2018) and genome instability adaptation in aggressive prostate cancer.